Management of acute (fulminant) liver failure

The term acute liver failure (ALF) is frequently applied as a generic
expression to describe patients presenting with or developing
an acute episode of liver dysfunction. In the context of
hepatological practice, however, ALF refers to a highly specific
and rare syndrome, characterised by an acute abnormality of liver
blood tests in an individual without underlying chronic liver disease.
The disease process is associated with development of a
coagulopathy of liver aetiology, and clinically apparent altered
level of consciousness due to hepatic encephalopathy. Several
important measures are immediately necessary when the patient
presents for medical attention. These, as well as additional clinical
procedures will be the subject of these clinical practice
guidelines.

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