Duke team IDs new target for fatty liver disease and prediabetes

By EASL May 17,2018

Scientists at Duke have identified a pathway in the liver that they believe could be manipulated to reduce the deposition of fat in the liver. It involves balancing two enzymes that work against each other to control fat metabolism. When they tried their method in rat models of obesity and metabolic disease, they found they could lower the amount of fat deposited in the liver and improve glucose regulation. They published their study in the journal Cell Metabolism.

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